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To prevent Conficker virus from infecting your Windows computer, you first need to disable the AutoRun feature. This can be done by downloading and installing certain updates manually for Windows XP or Windows 2000 . Windows Vista users can skip this step as this is taken care of via automatic updates . Now click Start , Run and enter gpedit.msc and click OK . Under Computer Configuration , expand Administrative Templates . Now for Windows XP, click System and for Windows Vista, click Windows Components then Autoplay Policies . In the Settings pane, right-click Turn off Autoplay , and then click Properties . Click Enabled , and then select All drives in the Turn off Autoplay box to disable Autorun on all drives. Click OK and restart the computer.